A Coq10 supplement is vital for people as they get older to maintain good health, especially for people on statins. Statins deplete Coq10 (that is how they work) to lower Cholesterol. The statins also stabilize plaques in arteries to prevent plaques from dislodging and clotting off an artery. Because the statins deplete your Coq10, it must be replaced, or it can cause dementia and other problems. CoQ10 is necessary, even in people not on statins, to help maintain good overall health, including brain health.