I have been taking both products, separately, for years, with good results. My wife, however, found herself exhausted by the end of the day, with barely enough energy to eat dinner and head off to bed. She eats well, exercises daily and gets plenty of sleep. I saw this product and something clicked--I felt that this might be the answer to her tiredness. She felt a measure of relief the first day, and the effects seem to have grown over time. We believe that her physical AND mental energy have improved substantially, especially toward the end of the day. This is an excellent formula, both effective and economical. She uses a scoop first thing in the morning, with choline, l-tyrosine, b complex and pqq.