Life Extension High Potency Optimized Folate – L-methylfolate – Folic Acid, 8500 mcg DFE – Heart & Brain Support, Healthy Homocysteine Levels – Gluten-Free, Non-GMO, Vegetarian – 30 Tablets

As a women of 72 yrs, I am focused on every element of my health, and had issues that indicated a need for folate. Only trust Life Extension quality and their scientific info. [This review was collected as part of a promotion.]

I learned this trick from Dr. Paul Saladino to take L-Methylfolate at night if you have genetic variants in the MTHFR and COMT. I often have issues with "wide awake" brain at bedtime as I'm not good at breaking down catecholamines including dopamine. This has been helping me sleep better immensely!!

My Doctor recommended this after my blood test showed low iron and a genetic malformation that doesn't allow my body to process regular iron supplements. After taking it less than a month my iron numbers nearly doubled. This will be something I take daily for the rest of my life.

Family member has MTHFR gene mutation and needs folate supplementation.

After taking this for a couple of weeks, I feel like I have more energy [This review was collected as part of a promotion.]

Much potency folate from high quality company; highly recommend. [This review was collected as part of a promotion.]

Help's keep down my homocysteine levels.

I was able to put contents of 14 bottles Into 1 bottle. All the additional plastic contributes to climate change and environnemental dégradation. [This review was collected as part of a promotion.]

optimized folate is a great product. The packaging, however, is terrible. They use a huge bottle for a tiny number of pills. I can literally combine ten bottles of this product into one. Unfortunately, this means loads of plastic in the landfill (our state doesn't have recycling for pill bottles). Please sell a larger number of pills per container and make the container size fit the product. It would be even better if you started a recycling program for your bottles!

Way too strong. I can't stress this enough. Any normal adult shouldn't ingest more than 1mg of methylfolate a day. That is the equivalent of 1000 mcg. The potency of these is 8500 mcg which is the equivalent of 8-1/2 mg methylfolate. After taking these for a few days, my husband and I started experiencing severe side effects including agitation, irritability, and especially joint aches. We both were having bad discomfort in our hips and lower back and we were unaware of what was causing these sudden attacks. When I read the list of over-methylation, and they all were on the list, we immediately stopped taking them. He waited a week before starting a normal dosed 1000 mcg methylfolate supplement. It has been a week and a half for me. I plan to use a pill cutter and take a quarter pill every 2 days within a week, skip a day, then start another round. So I'm telling everyone, they shouldn't be taking even 1 whole pill a week. It's not safe and will cause a series of health problems.