I take 1 pill every evening with supper. I absolutely love this product. Before taking this pill, I had been waking up 3 - 4 nights/week with excruciating hip pain. It was becoming unbearable. With only the 2nd pill, I had relief. It was a miracle. For the 1st time in over 6 months, I was able to sleep the night thru without awakening in pain. I also have a bad right knee. After awhile, I realized that my knee was no longer hurting me and I attribute that to the Turmeric also. This pill has changed my life - no more waking up in extreme hip pain plus I am able to exercise again now that my knee no longer hurts. Thank you Qunol!