This is the first time I've tried this product. In the initial weeks, I couldn't determine if there was any difference. I purchased it to help with my memory and energy, as I suffer from chronic fatigue syndrome (CFS) and fibromyalgia, which leave me feeling low on energy. Although I didn't notice a significant change at first, I did experience a slight improvement, which is a big deal for me. By week four, I felt that it was positively affecting my energy levels. I will definitely buy this again. I will give it a five-star rating when I can confirm that it continues to make a difference in my energy, memory, and skin. Even though I already have good skin for my age, I will update my review after my second purchase.