A doctor with MD %26 ND degrees said it would help with memory %26 cognition, so I've been taking one capsule daily for the last several yrs. I didn't have a neuro exam before, so don't have any way to compare, but I'm maintaining my memory %26 cognition at age 82. I will keep on ordering this supplement along with the other vitamin, mineral, %26 glucosamine supplements I've been taking for over 30 yrs. It's hard to assess cause %26 effect, of course, without a reliable, valid trial, but I just want to maintain good health as much as possible.