I have symptoms of estrogen dominance, so I thought I'd give this a try. Been taking this for a few months now, hoping that it would help me with some possible hormone related weight gain.I have lost 10 lbs in the past 6 months, but i don't think DIM is why. I also started working out more intensively, and counting calories.BUT there were some very nice surprises:My anxiety and panic attacks are back under control, after YEARS of hell. I even stopped taking my medication pretty easily (no withdrawals). I wonder if this might be the cause.My close friend, who suffers from acne, also tried it and said that her skin cleared up within a month.Most noticeably, for me, my periods used to arrive every 5 weeks. For 2 years or more (drs said it was stress), I was on a 5-week cycle. With horrible, building pms symptoms during that last week. And debilitating cramps.The first month I took DIM, I worried that something might be wrong when my period showed up after just 28 days. No major pms buildup, very light cramping. And it stayed that way. My cycle is now back to he way it was when I was younger. So I guess I'll keep taking it!